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Head & Neck Cancer

India bears the highest global burden of head and neck cancers. Our program combines de-intensification strategies with novel immunotherapy approaches.

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2,200+
New patients annually
68%
Organ preservation rate
1,200+
Genomic profiles completed
340
Multi-site trial enrollments

Research Themes

1

HPV-Negative Disease Biology

Genomic and epigenomic characterization of tobacco-driven head and neck cancers prevalent in the Indian population.

2

De-Intensification Strategies

Reducing treatment toxicity in favourable-prognosis patients through response-adapted radiation dose reduction.

3

Immunotherapy in Recurrent Disease

Evaluating novel checkpoint inhibitor combinations and tumour-infiltrating lymphocyte therapy for platinum-refractory cancers.

4

Swallowing & Speech Rehabilitation

Prospective studies on functional outcomes and quality of life after organ-preserving treatments.

Clinical Trials

NCT06234510

Recruiting

Nivolumab + Ipilimumab in Recurrent HPV-Negative HNSCC

PI: Dr. Arvind Krishnamurthy

NCT06234511

Active

Response-Adapted Radiation Dose Reduction in HPV+ Oropharyngeal Cancer

PI: Dr. Selvaluxmy Ganapathy

Support Head & Neck Cancer Research

Your contribution funds research into less toxic treatments that preserve speech, swallowing, and quality of life for patients with head and neck cancers.

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